Abstract - This interview actually concurs the concept
of innate immunity to HIV. The interviewee, Jay Levy from the University of
California talks about a particular aspect of the cellular immune response
known as CD8 cell antiviral factor which he
believes play an important role in successfully suppress the viral load of HIV
thereby limiting its progress. He also discuss the possibility that drug
manufacturing companies could perhaps develop a vaccine that could induce
similar effects on infected HIV-positive patients.
Abstract -- This articles shows that the innate immunity that some people have may be due to a
genetic defect that result in the absence of CCR5 receptor, the
receptor that HIV take advantage of to gain entrance into a host cell. Interestingly,
individuals who inherited a pair of the defected genes display apparent
immunity to HIV infection. While individuals who inherited only one of the
defected gene are not completely immune to HIV infection, they display
greater resistance to the progression of the virus.
Abstract -- This article attributed the ability to
keep the virus load in check to the ability of the immune system killer T cells
to recognize infected cells. Through a series of experiments, researchers have
found that the underlying ability of these HIV controllers (people who are able
to naturally suppress the viral load) may have to do with the unique protein
sequence of the killer T cell receptors. The researcher also discuss about the
possibility of developing a vaccine that could induce the production of these
effective killer T cells.
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